Weight LossInvestigational · Research use only
Tesofensine
Triple monoamine reuptake inhibitor (dopamine, serotonin, norepinephrine) originally developed for neurodegenerative disease, later studied for potent appetite suppression and weight loss.
Metabolic
Class
Weight Loss / Metabolic
Targets
Loading research profile
Evidence
1 linked resource
Related
Eloralintide · Cagrilintide
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Research overview
Benefits
- Significant appetite suppression
- Sustained weight loss
- Improved metabolic markers
- Enhanced satiety
Research side effects
- Research-use only; safety data in healthy humans is limited or absent.
- Nausea / GI upset
- Appetite suppression
- Diarrhea or constipation
- GI upset
Timing
Often studied with or before meals; protocols vary by compound.
Common research stacks
Semaglutide
Tirzepatide
RETATRUTIDE
AOD-9604
5-Amino-1MQ
Cagrilintide
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Studies & resources
Research reference only · Review source material independently · Not medical advice

